Flexible cotton-AuNP thread electrode for non-enzymatic sensor of uric acid in urine

We report on the development of an electrochemical sensor platform based modified cotton fibers for non-enzymatic detection uric acid (UA), important biomarker gout disease. To create flexible electrode, a thread was coated with carbon ink as pre-conductive layer prior to direct electrodeposition AuNPs. Then, differential pulse voltammetry (DPV) used evaluate performances, and linear range between 10 µM 5.0 mM obtained. The has limit 0.12 µM, which is sufficient use in patients suffering from disease higher than 4.46 mM. Furthermore, we found that sensitivity not affected by presence other physiological compounds present human urine. described potential integration diaper hence enabling rapid screening